Quantitative Extraction and Analysis of PFAS from Plastic Container Walls With Cut Coupons

U.S. Environmental Protection Agency (.gov)

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This document describes the laboratory procedures for sample preparation, analysis and
quantification of per- and polyfluoroalkyl substances (PFAS) in plastic (e.g., high-density
polyethylene (HDPE)) containers, by liquid chromatography with tandem mass spectrometry
(LC/MSMS).

The method may be used, with modifications, if necessary, for other similar types
of solid samples (e.g., fabric and packaging paper) for the analysis of PFAS. The full names and
the abbreviated names of all targeted PFAS analytes are listed in Table 1, along with their
Chemical Abstract Service Registry Number (CASRN).


Note: This method has been single lab validated at the Analytical Chemistry Branch (ACB) of
the Biological and Economic Analysis Division (BEAD), Office of Pesticide Programs (OPP). It
is recommended that the method be validated at each laboratory before use.

See the entire document: https://www.epa.gov/system/files/documents/2024-02/quantitative-extraction-and-analysis-of-pfas-from-plastic-container-walls-with-cut-coupons.pdf